09:00 - 10:00hRegistration 10:00 - 10:15hSequencing different levels of complexity (genomes, transcriptomes, epigenomes, transcriptomes): perspectives and data analysis challenges 10:15 - 11:30hMauno Vihinen: How can we make better predictors for variant interpretation? 11:50 - 13:05hSundar Venkataraman: The European Variation Archive: a database of genetic variation from all species 14:15 - 15:30hEmanuele Buratti: Pre-mRNA splicing predictions and phenotype analyses: from simple to complex disease contexts. 15:50 - 17:05h Montserrat Corominas: The regulatory genome of epithelial regeneration 17:05 - 17:20hPresentations of FEBS activities 17:20 - 17:35hShort Presentations from Participants 17:35 - 18:10hGeneral discussion
10:00 - 10:15hInferring the effect of variations on protein structure, stability and interactions. 10:15 - 11:30hPiero Fariselli: The effect of variations on protein stability and interactions 11:50 - 13:05hMarianne Rooman: Towards the prediction and interpretation of deleterious coding variants in terms of stability and functional features 14:15 - 15:30hYana Bromberg: Labeling tune-able protein positions for evaluating variation effects 15:50 - 17:05hZoya Ignatova: Position matters: roles for SNPs in protein biogenesis and function 17:05 - 17:35hShort presentations by School participants 17:35 - 18:10hGeneral discussion
10:00 - 10:15hFrom sequences to phenotype: is it possible to dissect the complexity of the relationship? 10:15 - 11:30hGianni Cesareni: Revealing and targeting the pathways that are perturbed in genetic diseases 11:50 - 13:05hLaura Furlong: DisGeNET: A discovery platform to support translational research on human diseases 14:15 - 15:30hSøren Brunak: Patient-past based precision medicine 15:50 - 17:05hAlfonso Valencia: the disease comorbidity network 17:05 - 17:35hShort Presentations from Participants 17:35 - 18:00hGeneral discussion and Closing remarks